Integrative Redox Biology Core

VanRemen2

Holly Van Remmen, PhD

Aging and Metabolism Research Program

Oklahoma Medical Research Foundation 

holly-vanremmen@omrf.org

Luke Szweda, Ph.D.

Luke Szweda, PhD

Aging and Metabolism Research Program

Oklahoma Medical Research Foundation 

luke-szweda@omrf.org

The Integrative Redox Biology Core of the Oklahoma Nathan Shock Center will provide investigators with a coordinated and comprehensive evaluation of the molecules, pathways, and systems that contribute to oxidative metabolism and oxidative stress using analyses of frozen samples from a wide variety of model species (e.g. invertebrates, rodents, exceptionally long-lived species, and humans). These analyses include state-of-the-art measures of redox and energy balance as well as oxidative damage and mitochondrial function. The Integrative Redox Biology Core will provide the following services:

Cost of Assays

 Assay 1: AMP, ADP, ATP, NADH, & NADPH  $25/sample
 Assay 2: NAD, NADP, CoAsH & Acetyl-CoA  $25/sample
 Assay 3: GSH & GSSG  $25/sample
 Assays 1 and 2  $40/sample
 Assays 1, 2, and 3  $50/sample
 F2-isoprostanes  $75/sample
 8-oxo-deoxy guanosine  $100/sample
 Protein carbonyls (total)  $25/sample
 Protein carbonyls (specific proteins)  $200/sample