Integrative Redox Biology Core

VanRemen2

Holly Van Remmen, PhD

Aging and Metabolism Research Program

Oklahoma Medical Research Foundation 

holly-vanremmen@omrf.org

The Integrative Redox Biology Core of the Oklahoma Nathan Shock Center will provide investigators with a coordinated and comprehensive evaluation of the molecules, pathways, and systems that contribute to oxidative metabolism and oxidative stress using analyses of frozen samples from a wide variety of model species (e.g. invertebrates, rodents, exceptionally long-lived species, and humans). These analyses include state-of-the-art measures of redox and energy balance as well as oxidative damage and mitochondrial function. The Integrative Redox Biology Core will provide the following services:

Cost of Assays

 Assay 1:NADH, & NADPH  $30/sample
 Assay 2: NAD, NADP  $30/sample
 Assay 3: GSH & GSSG  $30/sample
   
 F2-isoprostanes  $75/sample
 8-oxo-deoxy guanosine  $100/sample (not currently available)
 Protein carbonyls (total)  $75/sample
 Protein carbonyls (specific proteins)  $275/sample